Project 1: Investigation of the molecular basis of heterosis using proteomics and transcriptomics

Comparison of precision in proteomics versus transcriptomics

For our method of multiplexed proteomics using tandem mass tag (TMT) labeling, the median coefficient of variation (CV) between biological replicates was approximately 4-fold lower than that of transcriptomics. I visualized this difference in the violin plot below, which represents the CV of biological replicates from paired transcriptomic and proteomic datasets.

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